Compliant with INERIS DRC-09-103096 / EFSA 2020 — V9 Tier 3

EQRS V9 + ECOTOX V9
+ HUMAIN Module

The first French software integrating the human dietary pathway (food chain). Health risk assessment via ingestion of vegetables, eggs, milk, meat and fish grown or raised on a polluted site. PFAS, PCB, metals — EFSA 2020 TRVs.

International availability — this software relies on internationally recognized reference toxicological and physicochemical values (US EPA, ANSES, EFSA, INERIS, ECHA): it can be used for studies conducted in any country.

Features

The human dietary pathway, at last integrated

Full food chain

Soil → plant → animal → human transfer: leafy vegetables, root vegetables, eggs, milk, meat, fish. Bioconcentration and BCF/BTF transfer factors by substance.

PFAS, PCB, metals

Priority persistent pollutants: PFAS (PFOA/PFOS), dioxin-like PCB, lead, cadmium, mercury, arsenic — with EFSA 2020 TRVs (TWI) and toxic sums (TEQ).

DJE, QD & ERI by pathway

Daily exposure dose via the dietary pathway, hazard quotient and individual excess risk — accumulated by target organ per INERIS DRC-09-103096.

Monte Carlo & 70-year simulation

Uncertainty propagation across transfer and exposure parameters. Chronic exposure simulation over a 70-year lifetime.

Full 1-click PDF report

Technical file ready to submit to DDT / ARS: input data, transfer factors, DJE by pathway, QD/ERI by organ, calculation notes and adaptive conclusion.

Free 14-day demo

Full access to the HUMAIN Tier 3 module, no credit card required. Create your trial account to test the food chain on your own datasets.

Dietary exposure pathways

6 receptors of the food chain

The HUMAIN module models human ingestion of products from the site ecosystem, with soil→plant and plant/animal→animal transfer factors.

ReceptorModeled foodsExample substance
Leafy vegetablesLettuce, cabbage, spinachCadmium, lead, PFAS
Root vegetablesCarrot, potatoArsenic, PAH
EggsHens raised on-siteDioxin-like PCB, dioxins
MilkCows, grazing goatsPCB, PFAS, metals
MeatBeef, mutton, gamePCB, cadmium, lead
FishFish farming, local fishingPFAS, mercury (MeHg), PCB
Regulatory compliance

Regulatory framework

References applied

  • INERIS DRC-09-103096-09387C — accumulation of QD by target organ and ERI by carcinogenic effect (national methodology).
  • EFSA 2020 — Toxicological reference values (TRV/TWI) for PFAS (sum of the 4 PFAS: PFOA, PFOS, PFNA, PFHxS).
  • US-EPA RAGS Part A §8.2 / §8.3 — summation by organ / by cancer type.
  • ANSES 2018 — TRVs and IEM methodology (Interpretation of Environmental Media Status).
  • National contaminated sites methodology — MEEM/MTES 2017 (management plan, contaminated site management).
  • EU Regulation 2023/915 — regulatory maximum levels (PFAS, metals) in foodstuffs, for comparison.
Pricing

Choose your plan

Monthly

Flexible — cancel anytime

€660
incl. tax / month (€550 excl. tax)
  • Human dietary pathway (6 receptors)
  • PFAS, PCB, metals
  • Monte Carlo & 70-year simulation
  • 1-click PDF report
  • Email support
View monthly plan

HUMAIN module online — account access

The HUMAIN V9 Tier 3 module (concentration input, transfer factor calculation, DJE/QD/ERI by dietary pathway, Monte Carlo, PDF export) is accessible via the GMEP application after account creation. No installation required. Activate your free 14-day trial for full access, no credit card required.

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