NEW — ECOTOX V9 available

EQRS V9 + ECOTOX V9

The French HHRA + ERE reference. 104 substances for human health risk + 47 Tier 3 ecotox substances, a Tier 1, Tier 2 and Tier 3 approach, and 5 exclusive advanced modules: Monte Carlo, reverse calculation, 70-year temporal simulation, food chain and organ-based mixture. Compliant with INERIS ERS 2021, US EPA, ANSES, ECHA REACH and Sample & Suter.

International availability — this software relies on internationally recognized toxicological and physicochemical reference values (US EPA, ANSES, EFSA, INERIS, ECHA): it can be used for studies conducted in any country.

Overview

EQRS V9 — next-generation health risk assessment

104 parameterized substances, 22 interactive tabs, 14-page PDF report and native Leaflet mapping. All VTR come from the ANSES reference framework and are kept up to date.

104 substances

70 base substances + 30 emerging substances: PFAS following EU 2020 (20 substances), phthalates, flame retardants, recent pesticides and individual dioxins.

22 interactive tabs

Parameters, map location, threshold/non-threshold VTR, concentrations, J&E model, DJE, QD/ERI results, VLEP, and the 5 advanced modules.

14-page PDF report

Calculation notes, threshold and non-threshold VTR tables, QD/ERI detail by pathway and target, map location — ready to submit to the relevant authorities.

Leaflet 1.9.4 mapping

OSM / Plan IGN v2 / BD ORTHO base maps, Lambert 93 ↔ WGS84 conversion (proj4js), site and receptor markers, Domenico plume ellipse, PNG export.

NEW IN V9 — ECOTOX MODULE

Ecological risk (ERE) added to health risk (HHRA)

Where EQRS V9 assesses human health risk (QD, ERI, VLEP), ECOTOX V9 adds ecological risk via the PEC/PNEC quotient and food-chain transfers to wildlife — in the same interface.

Tier 1 — 7 sentinel receptors

PEC/PNEC quotient for soil (terrestrial plants, earthworm Eisenia fetida, micro-organisms), surface water (fish, daphnid D. magna, algae P. subcapitata) and groundwater (hyporheic macroinvertebrates).

Tier 2 — 5 trophic predators

Food-chain transfers (Sample & Suter ORNL/TM-13391) for 🐦 Robin, 🐭 Shrew, 🐹 Vole, 🦩 Heron and 🦦 Otter.

PNEC cascade

Hierarchical derivation of PNEC: INERIS → ECHA REACH (R.10) → US EPA Eco-SSL. 47 substances in V9: Pb, Cd, Zn, Cu, Ni, As, Hg, Cr VI, benzene, toluene, B(a)P, total PCB.

RQ color code

Readable Risk Quotient: 🟢 < 0.1 negligible, 🟠 < 1 low, 🔴 ≥ 1 potential — for each receptor and each substance.

Comparison

EQRS V9 + ECOTOX V9 vs MODUL'ERS vs RISC5

The only French tool combining HHRA (human) and ERE (ecological) in a single interface.

Criterion RISC5 MODUL'ERS (INERIS) EQRS V9 + ECOTOX V9
Last updated2014 (frozen)ActiveJune 2026
PlatformWindows desktopWindows + USB dongleWeb + Excel
Mandatory prior trainingRecommended2 days RC41None
Substances coveredUS EPA library~100 (INERIS)104 HHRA + 47 ECOTOX V9
PFAS EU 2020 (20 subst.)✗Partial✓
Reverse calculation (Cmax for target QD/ERI)Partial✗✓
Monte Carlo 1,000 drawsLimited✓✓ (+visual)
70-year temporal simulationPartial✓✓ DeVaull 2007
Human food chain✗✓✓ Trapp + Travis + INCA 3
Ecotoxicology Tier 1 + 2✗Partial✓ ECOTOX V9
PNEC cascade INERIS/ECHA/EPA✗INERIS only✓ Triple cascade
Leaflet + IGN + BRGM mapping✗Partial✓ native

Sources: INERIS MODUL'ERS, RISC5 User's Guide Nov 2014, substances.ineris.fr, ECHA REACH, US EPA Eco-SSL.

Regulatory compliance

Regulatory and scientific framework

References applied

  • INERIS ERS 2021 — national framework for health risk assessment (ICPE, ARR, IEM).
  • INERIS DRC-09-103096-09387C — cumulation of QD by target organ and ERI by carcinogenic effect.
  • INERIS DRC-08-94882 — ecological risk assessment (ERE) methodology.
  • US EPA RAGS Part A §8.2 / §8.3 — summation by organ / by cancer type.
  • US EPA Mixture Risk Assessment 2000 — mixture by target organ.
  • US EPA IRIS 2024 — 5 new carcinogenic ERU (PFOA, PFOS, DEHP, 2,3,7,8-TCDD, bromodichloromethane).
  • ANSES 2018 + INCA 3 — VTR, IEM methodology and dietary intake (food chain).
  • ECHA REACH Technical Guidance R.10 — PNEC derivation.
  • US EPA Eco-SSL OSWER 9285.7-55 — Ecological Soil Screening Levels.
  • Sample & Suter ORNL/TM-13391 — wildlife food-chain transfers.
  • OECD TG 201/202/203/207/208/222 — ecotoxicity tests.
  • OFB 2016 — hyporheic ESO/ESU parameters. National SSP methodology MEEM/MTES 2017.
Pricing

Subscribe to EQRS V9 + ECOTOX V9

Technical note — EQRS V9 + ECOTOX V9

Download the full technical note: architecture of the 22 tabs, HHRA and ERE methodology, scientific references and calculation examples.

Download the technical note (PDF)
Preview

Feature preview

interface · 22 tabs
Parameters VTR QD/ERI Ecotox
α (J&E) ......... 2.4 × 10⁻⁴
Σ QD child ...... 0.42
Σ ERI adult ..... 3.1 × 10⁻⁶
22-tab interface
monte-carlo · 1,000 draws
P95
Monte Carlo module

Median, P95, CV, P95/P50 ratio.

ecotox · Tier 1+2
🐦 Robin🟢 0.08
🐭 Shrew🟠 0.6
🦦 Otter🔴 1.4
🦩 Heron🟠 0.9
ECOTOX module
FAQ

Frequently asked questions — EQRS V9 + ECOTOX V9

What is EQRS (Évaluation Quantitative des Risques Sanitaires)?

EQRS quantifies health risks related to exposure to pollutant substances present on a site (soil, water, indoor air). It compares a Hazard Quotient (QD) to an Individual Excess Risk (ERI) to assess the acceptability of risks to exposed populations, as part of IEM procedures and contaminated site and soil management.

What is the difference between HHRA and ERE?

HHRA (Human Health Risk Assessment) evaluates risks to human health. ERE (Évaluation des Risques Écologiques) evaluates risks to ecosystems and sentinel receptors (PEC/PNEC, Eco-SSL). EQRS V9 + ECOTOX V9 is the only French software combining both approaches in a single platform.

Does the software comply with French regulatory frameworks?

Yes. Calculations comply with US EPA 2004, ANSES 2018, the INERIS ERS 2021 methodology, as well as ECHA REACH for PNEC and US EPA Eco-SSL. Regulatory updates are included in the subscription.

How many substances are taken into account?

104 substances for human health risk assessment (VOC, chlorinated solvents, PAH, metals, PFAS) and 47 ecotoxicological substances (Tier 3), in Tier 1 and Tier 2.

What are the 5 advanced modules?

The 5 exclusive advanced modules are: Monte Carlo sensitivity analysis, reverse calculation (admissible source concentration), 70-year temporal calculation, food chain, and target-organ mixture.

Can the PDF report be used for an administrative file?

Yes. The software generates a 14-page PDF report including calculation notes, VTR, and QD/ERI detail, ready to include in an IEM file or a contaminated site and soil management file intended for the administration (DDT, DREAL, ARS).

Do you offer a free trial?

Yes, a free 14-day trial is available with no installation, directly in the browser. No credit card is required to start the trial period.